1,3,5-Trimethoxybenzeneparari potest e1,3,5-tribromidebenzene et sodium methanolum in reactionibus catalysis a chloride cupro et methylo formato. Reagit cum N-bromosuccinimide in tetrachloride carbonii ad 2-bromo-1,3,5-trimethoxybenzene da. adhiberi potest ut vexillum internum spectri consectetuer NMR.
Una synthetica methodi 1,3,5-trimethoxybenzene ut mugiat;
1、 Misce 95% ethanolum et benzene cum 2,4,6-tribromobenzene, calore et dissolve; gradatim acidum sulphuricum concentratum ad 1—2 horas adde, move temperiem ad 50-60 gradus Celsium conservandum; adde NaNO2 in batches, coque per horas 2-3; refrigescant, sparguntur, lavant neutra, sicca ut solida 1,3,5-tribromobenzene possident.
2、mix 10g metalli sodium et 80ml methanolum sodium solutionis methanoli, adde 80ml dimethylformamideum, 2gCu2I2 et 20g1,3,5-tribromobenzenum, calefaciendo ad 90 gradus Celsius, refluxum reactionem excitans per 3 horas, filtrationem, pressuram filtratam methanolum et formamidei vaporis. destillatio vaporis vaporis, distillationis refrigerationis crystallizationis, filtationis, siccationis, scilicet1,3,5-trimethoxybenzene.
